Description

tert-Butyl(3-Butynyloxy)Diphenylsilane is a specialized organosilicon compound featuring a protected alkyne functionality. This unique structure makes it a versatile building block in advanced organic synthesis, particularly for applications requiring selective deprotection and further functionalization. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne handles for click chemistry or Sonogashira coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and herbicides where the silane-protected alkyne group allows for precise molecular assembly.
• Materials Science Research: Acts as a precursor for functionalized polymers, dendrimers, and advanced organic-inorganic hybrid materials.
• Chemical Biology Probes: Employed in the creation of tagged molecules and bioconjugates for diagnostic and research applications.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligand frameworks in organometallic chemistry and catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	tert-Butyl(3-Butynyloxy)Diphenylsilane
CAS No.	88158-68-3
Molecular Formula	C20H24OSi
Molecular Weight	308.49 g/mol
Synonyms	tert-Butyl(3-butyn-1-yloxy)diphenylsilane; Diphenyl-tert-butylsilyl 3-butynyl ether; 3-[(tert-Butyldiphenylsilyl)oxy]-1-propyne; (3-Butynyloxy)(tert-butyl)diphenylsilane; TBDPSO-protected propargyl alcohol; tert-Butyldiphenyl(3-butynyloxy)silane; Silane, tert-butyl(3-butynyloxy)diphenyl-
EINECS	Contact for details

Quality Control

Our tert-Butyl(3-Butynyloxy)Diphenylsilane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.