Description

Ethyl4-[2-(1,3-Dioxo-1,3-Dihydro-2H-Isoindol-2-Yl)Ethoxyl]-3-Oxobutanoate is a specialized organic compound featuring a phthalimide moiety linked to a β-ketoester functional group via an ethoxy spacer. This unique bifunctional structure makes it a valuable high-purity building block for advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phthalimide-protected amine functionalities or β-ketoester motifs for further cyclization.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators that leverage its reactive ester and ketone groups.
• Peptidomimetic Research: Serves as a scaffold in medicinal chemistry for creating peptide analogs and protease inhibitors, where the phthalimide group can act as a protecting group or a pharmacophore.
• Polymer Chemistry: Potential monomer or cross-linking agent for specialty polymers, utilizing its multiple reactive sites for polymerization or post-polymerization modification.
• Material Science: Intermediate in the development of organic electronic materials, dyes, and photoactive compounds.
• Academic & Contract Research: A versatile reagent for methodological development and exploring new chemical reactions in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	Ethyl4-[2-(1,3-Dioxo-1,3-Dihydro-2H-Isoindol-2-Yl)Ethoxyl]-3-Oxobutanoate
CAS No.	88150-75-8
Molecular Formula	C₁₆H₁₇NO₆
Molecular Weight	319.31 g/mol
Synonyms	Ethyl 4-[2-(1,3-dioxoisoindolin-2-yl)ethoxy]-3-oxobutanoate; 2-[2-(2-Ethoxy-2-oxoethyl)-3-oxobutoxy]isoindoline-1,3-dione; Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate; 88150-75-8; Butanoic acid, 4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxo-, ethyl ester; N-(2-Carbethoxy-3-oxopropyl)phthalimide ethyl ether (related structure).
EINECS	Contact for details

Quality Control

Our Ethyl4-[2-(1,3-Dioxo-1,3-Dihydro-2H-Isoindol-2-Yl)Ethoxyl]-3-Oxobutanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.