Description

5-Bromo-2-Hydroxymethylpyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a bromine substituent and a hydroxymethyl group, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Bromo-2-Hydroxymethylpyridine
CAS No.	88139-91-7
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	2-(Hydroxymethyl)-5-bromopyridine; (5-Bromo-2-pyridyl)methanol; 5-Bromo-2-pyridinemethanol; 5-Bromo-2-(hydroxymethyl)pyridine; 5-Bromo-2-pyridylcarbinol; 88139-91-7; 5-Br-2-HMP
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxymethylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.