Description

4-Bromo-2-Fluorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for the synthesis of complex organic molecules. Its core value lies in enabling the efficient introduction of the isocyanate functional group, which is pivotal for creating ureas, carbamates, and other heterocyclic compounds. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredient development and fine chemical production.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its halogenated aromatic structure contributes to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes and polymers with specific thermal or chemical resistance properties.
• Material Science Research: Employed in creating functionalized surfaces, coatings, and advanced materials that require specific isocyanate-based coupling.
• Chemical Biology & Proteomics: Acts as a reagent for labeling and modifying biomolecules, facilitating studies in protein interaction and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Bromo-2-Fluorophenyl Isocyanate
CAS No.	88112-75-8
Molecular Formula	C7H3BrFNO
Molecular Weight	216.01 g/mol
Synonyms	2-Fluoro-4-bromophenyl isocyanate; 1-Bromo-3-fluoro-4-isocyanatobenzene; 4-Bromo-2-fluorophenyl isocyanate; Isocyanic acid, 4-bromo-2-fluorophenyl ester; (4-Bromo-2-fluorophenyl)isocyanate; 4-Bromo-2-fluoro-1-isocyanatobenzene; 2-Fluoro-4-bromo-1-isocyanatobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorophenyl Isocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against stringent in-house specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.