Description

3-Cyclopentene-1,2-Diol, 5-(Hydroxymethylamino)-4-2-(Phenylthio)Ethenyl-, 1,2-Diacetate, 1S-1.Alpha.,2.Beta.,4(E),5.Beta.- is a sophisticated chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring complex stereochemistry.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic applications.
• Process Chemistry Development: Serves as a benchmark or key component in scaling up synthetic routes from laboratory to pilot plant scale.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, agrochemicals, and other high-value, low-volume products.

Basic Information

Product Name	3-Cyclopentene-1,2-Diol, 5-(Hydroxymethylamino)-4-2-(Phenylthio)Ethenyl-, 1,2-Diacetate, 1S-1.Alpha.,2.Beta.,4(E),5.Beta.-
CAS No.	88111-93-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,2R,4E,5R)-5-[(Hydroxymethyl)amino]-4-[2-(phenylsulfanyl)ethenyl]cyclopent-4-ene-1,2-diyl diacetate; 1S-1α,2β,4(E),5β- Isomer of the diacetate derivative; 5-(Hydroxymethylamino)-4-[2-(phenylthio)ethenyl]-3-cyclopentene-1,2-diol 1,2-diacetate; Chiral cyclopentene diol diacetate derivative; Phenylthio ethenyl cyclopentene intermediate; Advanced pharmaceutical building block; Specialty chiral synthon.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and related substances are available upon request. We adhere to a cGMP-compliant quality management system for products destined for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.