Description

Methyl 5-Iodothiophene-2-Carboxylate is a high-purity iodinated thiophene derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, serving as a key intermediate for constructing complex heterocyclic systems and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs), specialty chemicals, and organic electronic components.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for enhanced biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Ligand & Catalyst Development: The iodine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira), making it valuable for creating specialized ligands and catalysts.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry, medicinal chemistry, and the exploration of new chemical entities.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fine chemicals and specialty additives.

Basic Information

Item	Details
Product Name	Methyl 5-Iodothiophene-2-Carboxylate
CAS No.	88105-22-0
Molecular Formula	C6H5IO2S
Molecular Weight	268.07 g/mol
Synonyms	Methyl 5-iodo-2-thiophenecarboxylate; 5-Iodothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 5-iodo-, methyl ester; Methyl 5-iodothiophene-2-carboxylate; 5-Iodo-2-thiophenecarboxylic acid methyl ester; Methyl 5-iodo-2-thiophenecarboxylate; 88105-22-0; Methyl 5-iodothiophene-2-carboxylic acid ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Iodothiophene-2-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications to guarantee identity, purity, and consistency for your synthetic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.