Description

Tetrahydro-1H-Pyrrolizine-7A(5H)-Acetic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic frameworks and fused ring systems.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities with potential therapeutic activity.
• Fine Chemical Production: Serves as a specialized raw material for the manufacture of high-value, low-volume specialty chemicals.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	Tetrahydro-1H-Pyrrolizine-7A(5H)-Acetic Acid Ethyl Ester
CAS No.	88069-56-1
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	Ethyl 1,2,3,6,7,7a-hexahydro-1H-pyrrolizine-7a-carboxylate; 7a-Ethoxycarbonylhexahydropyrrolizine; 7a-Carbethoxyhexahydropyrrolizine; Hexahydropyrrolizine-7a-carboxylic acid ethyl ester; Ethyl hexahydro-1H-pyrrolizine-7a-carboxylate; 1H-Pyrrolizine-7a(5H)-acetic acid, ethyl ester, hexahydro-; (7aS)-Hexahydro-1H-pyrrolizine-7a-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Tetrahydro-1H-Pyrrolizine-7A(5H)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.