Description

4-(1-Isocyano-Ethyl)-Pyridine is a versatile organic building block featuring both a reactive isocyano group and a pyridine ring. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex heterocyclic compounds and functional materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating libraries of nitrogen-containing heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the pyridine and isonitrile functionalities can be leveraged to create active ingredients with specific modes of action.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of specialized ligands and catalysts, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers, coordination polymers (MOFs), and functional surfaces.
• Chemical Biology Probes: Utilized in the creation of isonitrile-based probes for studying biological processes and enzyme activities due to its bio-orthogonal reactivity.

Basic Information

Product Name	4-(1-Isocyano-Ethyl)-Pyridine
CAS No.	87869-17-8
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	1-(4-Pyridyl)ethyl isocyanide; 4-(1-Isocyanoethyl)pyridine; 4-(Isocyanomethyl)pyridine (common misnomer); 4-Pyridineethanenitrile, α-(isocyanomethyl)-; α-Isocyanoethylpyridine; p-(1-Isocyanoethyl)pyridine; Isocyanomethyl pyridine derivative
EINECS	Contact for details

Quality Control

Our 4-(1-Isocyano-Ethyl)-Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and IR spectroscopy. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be sensitive to moisture and prolonged exposure to air. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.