Description

5-(tert-Butyldimethylsilyloxy)Pentanoic Acid is a high-purity, protected carboxylic acid derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group. This compound is a critical synthetic intermediate valued for its role in constructing complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the controlled introduction of functionalized pentanoic acid chains.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a protected hydroxyl functionality.
• Peptide & Prostaglandin Synthesis: Used in the preparation of peptide mimetics and lipid-based bioactive molecules like prostaglandin analogs.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers with tailored surface properties.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Cross-Coupling Reactions: The carboxylic acid group can be further derivatized for use in metal-catalyzed coupling reactions to form carbon-carbon bonds.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of organic electronic materials requiring specific chain lengths and protected polar groups.

Basic Information

Product Name	5-(tert-Butyldimethylsilyloxy)Pentanoic Acid
CAS No.	87729-39-3
Molecular Formula	C11H24O3Si
Molecular Weight	232.40 g/mol
Synonyms	5-[(tert-Butyldimethylsilyl)oxy]pentanoic acid; 5-(TBDMS-oxy)valeric acid; 5-Hydroxypentanoic acid TBDMS ether; 5-[(1,1-Dimethylethyl)dimethylsilyl]oxy]pentanoic acid; 5-O-(tert-Butyldimethylsilyl)pentanoic acid; Valeric acid, 5-[(tert-butyldimethylsilyl)oxy]-; 87729-39-3; Pentanoic acid, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyldimethylsilyloxy)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.