Description

5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-pentanoic acid methyl ester is a protected ester derivative of a hydroxypentanoic acid, featuring a tert-butyldimethylsilyl (TBDMS) ether group. This compound is a critical synthetic intermediate valued for its role in multi-step organic synthesis, where the silyl protecting group provides stability under a wide range of reaction conditions. It is primarily utilized by pharmaceutical, agrochemical, and advanced material research sectors for the production of complex molecules, including active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a protected synthon for introducing pentanoic acid derivatives in multi-step reactions.
• Peptide & Polymer Chemistry: Employed in the synthesis of modified peptides and as a monomer or modifier for specialty polymers.
• Material Science Research: Used in the development of novel organic materials and liquid crystals.
• Flavor & Fragrance Industry: Intermediate for the synthesis of specific ester-based aroma compounds.

Basic Information

Item	Details
Product Name	5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-pentanoic acid methyl ester
CAS No.	87729-38-2
Molecular Formula	C13H28O3Si
Molecular Weight	260.45 g/mol
Synonyms	Methyl 5-[(tert-butyldimethylsilyl)oxy]pentanoate; Methyl 5-((tert-butyldimethylsilyl)oxy)valerate; 5-(tert-Butyldimethylsilyloxy)pentanoic acid methyl ester; 5-[(TBDMS)oxy]pentanoic acid methyl ester; 5-O-(tert-Butyldimethylsilyl)pentanoic acid methyl ester; TBDMS-protected methyl 5-hydroxypentanoate; Methyl 5-hydroxyvalerate TBDMS ether
EINECS	Contact for details

Quality Control

Our production of 5-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-pentanoic acid methyl ester adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality management system supports the demands of GMP and ISO standards for critical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.