Description

2-Acetyl-3-Fluoropyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role in introducing both acetyl and fluorine functional groups, which are pivotal for modulating the biological activity and physicochemical properties of target molecules. It is primarily needed by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients, including potential kinase inhibitors and other small-molecule therapeutics.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly kinase inhibitors.
• Building block for advanced agrochemicals and crop protection agents.
• Precursor in material science for creating functionalized ligands and organic electronic materials.
• Versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Used in the research and development of fluorinated analogs for metabolic stability enhancement.
• Starting material for the synthesis of complex heterocyclic compounds in fine chemical production.

Basic Information

Product Name	2-Acetyl-3-Fluoropyridine
CAS No.	87674-20-2
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	1-(3-Fluoropyridin-2-yl)ethanone; 3-Fluoro-2-acetylpyridine; 2-Acetyl-3-fluoropyridine; 1-(3-Fluoro-2-pyridinyl)ethanone; Ethanone, 1-(3-fluoro-2-pyridinyl)-; 3-Fluoropyridine-2-carbaldehyde, acetyl derivative
EINECS	Contact for details

Quality Control

Our 2-Acetyl-3-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.