Description

2-Bromonicotinamide is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen site and a functionalizable amide group, enabling the construction of complex nitrogen-containing heterocycles. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with pyridine-based core structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	2-Bromonicotinamide
CAS No.	87674-18-8
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	2-Bromo-3-pyridinecarboxamide; 2-Bromopyridine-3-carboxamide; Nicotinamide, 2-bromo-; 3-Pyridinecarboxamide, 2-bromo-; 2-Bromo-nicotinamide; 2-Bromonicotinic acid amide
EINECS	Contact for details

Quality Control

Our 2-Bromonicotinamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.