Description

1-(3-Fluoro-Pyridin-4-Yl)-Ethanol is a versatile fluorinated pyridine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the hydroxyl group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluoropyridine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags and molecular probes for diagnostic and research applications.

Basic Information

Product Name	1-(3-Fluoro-Pyridin-4-Yl)-Ethanol
CAS No.	87674-15-5
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	4-(1-Hydroxyethyl)-3-fluoropyridine; 3-Fluoro-4-(1-hydroxyethyl)pyridine; 1-(3-Fluoropyridin-4-yl)ethanol; 1-(3-Fluoro-4-pyridinyl)ethanol; α-Methyl-3-fluoro-4-pyridinemethanol
EINECS	Contact for details

Quality Control

Our 1-(3-Fluoro-Pyridin-4-Yl)-Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Enantiomerically Enriched)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.