Description

2-Bromomethyl-3-Hydroxypyridine Hydrobromide is a versatile and high-purity chemical intermediate crucial for advanced organic synthesis. Its primary value lies in its functionalized pyridine core, which serves as a key building block for constructing complex molecules in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive bromomethyl and hydroxypyridine groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where the pyridine moiety is required.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.
• Academic and R&D Laboratories: Used in universities and research institutes for methodological development and exploring new chemical entities.

Basic Information

Product Name	2-Bromomethyl-3-Hydroxypyridine Hydrobromide
CAS No.	87440-88-8
Molecular Formula	C6H7Br2NO
Molecular Weight	268.94 g/mol
Synonyms	3-Hydroxy-2-(bromomethyl)pyridine hydrobromide; 2-(Bromomethyl)-3-hydroxypyridine hydrobromide; 3-Hydroxy-2-pyridinemethanol, bromo-, hydrobromide; 2-Bromomethyl-3-pyridinol hydrobromide; (3-Hydroxy-2-pyridyl)methyl bromide hydrobromide; Pyridine, 2-(bromomethyl)-3-hydroxy-, hydrobromide
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-3-Hydroxypyridine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.