Description

cis-3,3-Dichloro-3,3A,6,6A-Tetrahydro-2H-Cyclopenta[B]Furan-2-One is a high-purity, specialized organic intermediate characterized by its unique fused bicyclic lactone structure containing chlorine substituents. This compound is valued for its precise stereochemistry and functional groups, which make it a critical building block in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides and insecticides, leveraging its halogenated cyclic framework.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials requiring specific rigid, functionalized monomers.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the study and development of new asymmetric catalytic reactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cycloaddition and functional group transformation research.

Basic Information

Product Name	cis-3,3-Dichloro-3,3A,6,6A-Tetrahydro-2H-Cyclopenta[B]Furan-2-One
CAS No.	87411-55-0
Molecular Formula	C7H6Cl2O2
Molecular Weight	193.03 g/mol
Synonyms	cis-3,3-Dichloro-3a,4,7,7a-tetrahydro-4,7-epoxyisobenzofuran-1(3H)-one; 3,3-Dichlorohexahydro-4,7-epoxyisobenzofuran-1(3H)-one; 3,3-Dichloro-3a,4,7,7a-tetrahydro-4,7-epoxyisobenzofuran-1(3H)-one; 3,3-Dichloro-3a,4,7,7a-tetrahydro-4,7-epoxy-1H-isobenzofuran-1-one; 3,3-Dichloro-4,7-epoxyisobenzofuran-1(3H)-one, hexahydro-; (3aR,4S,7R,7aS)-3,3-Dichlorohexahydro-4,7-epoxyisobenzofuran-1(3H)-one; (3aR,4S,7R,7aS)-3,3-Dichloro-3a,4,7,7a-tetrahydro-4,7-epoxyisobenzofuran-1(3H)-one
EINECS	Contact for details

Quality Control

Our cis-3,3-Dichloro-3,3A,6,6A-Tetrahydro-2H-Cyclopenta[B]Furan-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.