Description

1-(3-Bromopyridin-2-Yl)Piperazine is a versatile brominated heterocyclic building block of significant importance in modern organic synthesis and pharmaceutical research. Its core value lies in its bifunctional structure, featuring both a piperazine ring and a brominated pyridine moiety, which makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets, kinase inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a valuable building block for creating chelating ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Employed in the design of linker molecules and degraders for targeted protein degradation research.
• Material Science Research: Intermediate for synthesizing functional polymers, dyes, and electronic materials requiring specific nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from gram to kilogram quantities.

Basic Information

Product Name	1-(3-Bromopyridin-2-Yl)Piperazine
CAS No.	87394-56-7
Molecular Formula	C9H12BrN3
Molecular Weight	242.12 g/mol
Synonyms	1-(3-Bromo-2-pyridinyl)piperazine; 2-(1-Piperazinyl)-3-bromopyridine; 3-Bromo-2-(piperazin-1-yl)pyridine; 3-Bromo-2-piperazin-1-ylpyridine; 1-(3-Bromopyridin-2-yl)piperazine; Piperazine, 1-(3-bromo-2-pyridinyl)-; 87394-56-7 (CAS)
EINECS	Contact for details

Quality Control

Our 1-(3-Bromopyridin-2-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.