Description

1-(3-Chloropyridin-2-Yl)Piperazine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound is a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique piperazine-pyridine scaffold enables the creation of molecules with targeted biological activity. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, high-value compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal catalysis and other synthetic methodologies.
• Fine Chemical Production: An essential building block for the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	1-(3-Chloropyridin-2-Yl)Piperazine
CAS No.	87394-55-6
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	1-(3-Chloro-2-pyridinyl)piperazine; 2-(Piperazin-1-yl)-3-chloropyridine; 3-Chloro-2-(piperazin-1-yl)pyridine; 1-(3-Chloro-pyridin-2-yl)-piperazine; 87394-55-6; 1-(3-Chloro-2-pyridyl)piperazine; 3-Chloro-2-piperazin-1-ylpyridine
EINECS	Contact for details

Quality Control

Our 1-(3-Chloropyridin-2-Yl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.