Description

4-(Benzylamino)-2-Chloronicotinonitrile is a versatile and high-value chemical intermediate characterized by its unique chloronicotinonitrile core functionalized with a benzylamino group. This compound matters for its role as a critical building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for creating novel active ingredients, as well as by agrochemical manufacturers developing new crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, insecticides, and fungicides with improved efficacy.
• Chemical Research & Development: Used in academic and industrial labs for exploring new heterocyclic chemistry and creating specialized compound libraries.
• Material Science: Potential intermediate in the development of organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-(Benzylamino)-2-Chloronicotinonitrile
CAS No.	87243-49-0
Molecular Formula	C13H10ClN3
Molecular Weight	243.69 g/mol
Synonyms	2-Chloro-4-(benzylamino)nicotinonitrile; 4-(Benzylamino)-2-chloropyridine-3-carbonitrile; 2-Chloro-4-(phenylmethylamino)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 2-chloro-4-[(phenylmethyl)amino]-; 87243-49-0; 4-Benzylamino-2-chloronicotinonitrile; 2-Chloro-4-benzylaminonicotinonitrile
EINECS	Contact for details

Quality Control

Our 4-(Benzylamino)-2-Chloronicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.