Description

Benzyl (S)-(-)-Tetrahydro-5-Oxo-3-Furanylcarbamate is a high-purity chiral building block and pharmaceutical intermediate of significant commercial and research interest. Its core value lies in its stereochemically defined structure, which is essential for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by R&D laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutics and high-value chemical products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-infective agents.
• Asymmetric Synthesis: Serves as a versatile precursor for introducing the (S)-tetrahydro-5-oxo-3-furanyl moiety in catalytic asymmetric transformations and multi-step synthetic routes.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to its structural similarity to transition-state analogs.
• Agrochemical Active Ingredient Development: Employed in the research phase for creating novel, enantiopure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing chiral ligands and organocatalysts used in stereoselective reactions.
• Academic and Industrial R&D: A valuable compound for methodological studies in organic chemistry and for scaling up patented synthetic processes.

Basic Information

Product Name	Benzyl (S)-(-)-Tetrahydro-5-Oxo-3-Furanylcarbamate
CAS No.	87219-29-2
Molecular Formula	C13H15NO4
Molecular Weight	249.26 g/mol
Synonyms	(S)-Benzyl 5-oxotetrahydrofuran-3-ylcarbamate; (3S)-Tetrahydro-5-oxo-3-furanyl carbamic acid benzyl ester; Benzyl N-[(3S)-5-oxotetrahydro-3-furanyl]carbamate; (S)-(-)-Benzyl tetrahydro-5-oxo-3-furancarbamate; (S)-Benzyl 5-oxooxolan-3-ylcarbamate; (3S)-5-Oxotetrahydrofuran-3-yl carbamic acid benzyl ester; (S)-Benzyl 5-oxotetrahydro-2-furanylcarbamate; Benzyl (S)-5-oxotetrahydrofuran-3-ylcarbamate
EINECS	Contact for details

Quality Control

Our Benzyl (S)-(-)-Tetrahydro-5-Oxo-3-Furanylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical R&D and advanced synthesis. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.