Description

5-Ethyl-5-(1-Ethylpropyl)-2-Thiobarbituric Acid is a specialized thiobarbiturate derivative, a class of compounds known for their significant role in pharmaceutical research and development. This compound matters as a key synthetic intermediate and reference standard for the development of central nervous system (CNS) acting drugs and analytical methodologies. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on neuropharmacology, anesthesiology, and analytical chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel barbiturate and thiobarbiturate analogs for pharmacological evaluation.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and validation.
• Neuroscience Research: Employed in biochemical studies to investigate the structure-activity relationships (SAR) of compounds interacting with GABAA receptors.
• Chemical Synthesis: Acts as a precursor for the preparation of more complex heterocyclic compounds with potential biological activity.
• Academic Research: Utilized in university and institutional labs for teaching and advanced studies in medicinal chemistry and organic synthesis.

Basic Information

Product Name	5-Ethyl-5-(1-Ethylpropyl)-2-Thiobarbituric Acid
CAS No.	87171-21-9
Molecular Formula	C11H18N2O2S
Molecular Weight	242.34 g/mol
Synonyms	5-Ethyl-5-(1-ethylpropyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 5-Ethyl-5-(1-ethylpropyl)-2-thiobarbituric acid; 2-Thio-5-ethyl-5-(1-ethylpropyl)barbituric acid; Thiobarbituric acid derivative (C11); NSC 3364; 5-Ethyl-5-(pentan-3-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Ethylpropyl)-2-Thiobarbituric Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.