Description

Pyridine, 2-Chloro-5-(Phenylethynyl)- is a specialized halogenated and alkynyl-substituted pyridine derivative, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced material science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with enhanced activity.
• Material Science: Serves as a precursor for ligands in catalytic systems and as a monomer for conductive polymers in organic electronics.
• Chemical Research: Valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Used to prepare complex chelating agents for metal-organic frameworks (MOFs) and coordination chemistry.
• Fluorescent Probe Development: The conjugated system can be utilized in the design of sensors and imaging agents.

Basic Information

Product Name	Pyridine, 2-Chloro-5-(Phenylethynyl)-
CAS No.	87148-60-5
Molecular Formula	C13H8ClN
Molecular Weight	213.66 g/mol
Synonyms	2-Chloro-5-(phenylethynyl)pyridine; 5-(Phenylethynyl)-2-chloropyridine; 2-Chloro-5-(2-phenylethynyl)pyridine; 2-Chloro-5-(phenylethinyl)pyridine; (2-Chloropyridin-5-yl)(phenyl)ethyne
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Chloro-5-(Phenylethynyl)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by NMR, HPLC, and GC-MS to confirm identity and purity. Certificates of Analysis (COA) detailing all analytical results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.