Description

2-Chloro-4-Propionylpyridine is a versatile pyridine derivative and a key organic building block. Its molecular structure, featuring both a chloro and a propionyl substituent, makes it a valuable intermediate for synthesizing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. It serves as a crucial precursor in the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core is a common structural motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Research & Development: A versatile building block for organic synthesis, enabling the introduction of both halogen and ketone functional groups in molecular design.

Basic Information

Product Name	2-Chloro-4-Propionylpyridine
CAS No.	87121-53-7
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	1-(2-Chloro-4-pyridinyl)-1-propanone; 2-Chloro-4-propionyl pyridine; 4-Acetyl-2-chloropyridine (common misnomer); 2-Chloro-4-propanoylpyridine; 4-Propanoyl-2-chloropyridine; 2-Chloro-4-(1-oxopropyl)pyridine; 2-Chloro-4-pyridyl ethyl ketone
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Propionylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.