Description

4,4,4-Trifluoro-Butyric Acid Isopropyl Ester is a high-purity fluorinated ester building block essential for advanced chemical synthesis. Its value lies in the unique reactivity and properties imparted by the trifluoromethyl group, enabling the development of novel materials and active compounds. This product is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for applications requiring fluorine incorporation.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to introduce fluorine into polymer chains, enhancing properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Building Block: Utilized in various organic reactions, including esterifications, transesterifications, and as a source of the 4,4,4-trifluorobutyl moiety in complex molecule assembly.
• Surface Active Agent Precursor: Acts as an intermediate for manufacturing fluorinated surfactants and coatings with low surface energy.

Basic Information

Product Name	4,4,4-Trifluoro-Butyric Acid Isopropyl Ester
CAS No.	86994-27-6
Molecular Formula	C7H11F3O2
Molecular Weight	184.16 g/mol
Synonyms	Isopropyl 4,4,4-trifluorobutyrate; 4,4,4-Trifluorobutanoic Acid Isopropyl Ester; 1-Methylethyl 4,4,4-Trifluorobutanoate; 4,4,4-Trifluorobutyric Acid 1-Methylethyl Ester; 4,4,4-Trifluorobutanoic Acid 1-Methylethyl Ester; Isopropyl 4,4,4-Trifluorobutanoate; 86994-27-6; Propanoic acid, 3,3,3-trifluoro-, 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-Butyric Acid Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.365 - 1.375
Density (20°C)	1.15 - 1.25 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.