Description

(R)-(+)-3-(Acetylthio)Isobutyric Acid Methyl Ester CAS NO 86961-07-1 is a high-purity chiral building block and key synthetic intermediate. This compound is valued for its role in the stereoselective synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of angiotensin-converting enzyme (ACE) inhibitors and other cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, enhancing efficacy and environmental profile.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Bioconjugation & Proteomics: The acetylthio group can be utilized for site-specific protein labeling and modification studies.
• Material Science: Acts as a monomer or modifier in the synthesis of polymers with tailored properties.

Basic Information

Product Name	(R)-(+)-3-(Acetylthio)Isobutyric Acid Methyl Ester
CAS No.	86961-07-1
Molecular Formula	C7H12O3S
Molecular Weight	176.23 g/mol
Synonyms	Methyl (R)-3-(Acetylthio)-2-methylpropanoate; (R)-Methyl 3-(Acetylthio)-2-methylpropionate; (R)-(+)-3-(Acetylmercapto)-2-methylpropionic Acid Methyl Ester; (R)-3-Acetylthio-2-methylpropionic Acid Methyl Ester; (R)-ATME; (R)-Acetylthioisobutyric Acid Methyl Ester; (R)-Acetylthio-2-methylpropanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (R)-(+)-3-(Acetylthio)Isobutyric Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and GC/HPLC for chemical purity, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.