Description

2-Hydroxymethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester is a versatile chiral building block and protected amino acid derivative of significant importance in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a protected carboxylic acid and a hydroxymethyl group, which allows for selective modifications and incorporation into complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals.

Application

• As a key chiral intermediate in the multi-step synthesis of pharmaceutical compounds and active pharmaceutical ingredients (APIs).
• For the construction of peptidomimetics and modified peptide structures in medicinal chemistry research.
• As a building block in the development of novel catalysts and ligands for asymmetric synthesis.
• In the preparation of specialized monomers for polymer and material science applications.
• As a starting material or intermediate for custom synthesis and contract manufacturing services.

Basic Information

Product Name	2-Hydroxymethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester
CAS No.	86954-05-4
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-(hydroxymethyl)pyrrolidine; (2-Hydroxymethyl-1-pyrrolidinyl)-carboxylic Acid Benzyl Ester; 2-(Hydroxymethyl)-1-pyrrolidinecarboxylic Acid Phenylmethyl Ester; Cbz-2-(Hydroxymethyl)pyrrolidine; N-Cbz-2-(Hydroxymethyl)pyrrolidine; 1-Cbz-2-(Hydroxymethyl)pyrrolidine; Benzyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-Pyrrolidine-1-Carboxylic Acid Benzyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.