Description

2-Cyano-5-Hydroxypyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a cyano and a hydroxyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine-based core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing cyano group.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biochemical research.

Basic Information

Product Name	2-Cyano-5-Hydroxypyridine
CAS No.	86869-14-9
Molecular Formula	C6H4N2O
Molecular Weight	120.11 g/mol
Synonyms	5-Hydroxy-2-cyanopyridine; 5-Hydroxypicolinonitrile; 2-Pyridinecarbonitrile, 5-hydroxy-; 5-Hydroxy-2-pyridinecarbonitrile; 2-Cyano-5-pyridinol
EINECS	Contact for details

Quality Control

Our 2-Cyano-5-Hydroxypyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the rigorous standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.