Description

3-Pyridinecarboxylicacid,2-Amino-6-Fluoro-,2-Propynylester(9Ci) is a specialized fluorinated pyridine derivative that serves as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines an amino-fluoro substitution pattern with a propargyl ester moiety, enabling precise structural modifications for targeted applications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, where the fluorine atom and pyridine core contribute to enhanced biological activity and environmental stability.
• Chemical Biology Probe Synthesis: Employed to create tagged or functionalized molecules for studying biological pathways and protein interactions, leveraging the reactive alkyne group for click chemistry.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of advanced polymers and specialty materials with tailored properties.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	3-Pyridinecarboxylicacid,2-Amino-6-Fluoro-,2-Propynylester(9Ci)
CAS No.	86724-91-6
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	2-Amino-6-fluoronicotinic acid propargyl ester; Propargyl 2-amino-6-fluoropyridine-3-carboxylate; 2-Amino-6-fluoro-3-pyridinecarboxylic acid 2-propynyl ester; 2-Amino-6-fluoronicotinic acid 2-propynyl ester; 86724-91-6; 2-Propynyl 2-amino-6-fluoropyridine-3-carboxylate; 2-Amino-6-fluoro-3-(prop-2-yn-1-yloxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarboxylicacid,2-Amino-6-Fluoro-,2-Propynylester(9Ci) is produced and tested under a strict quality management system to ensure consistency and reliability for critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.