Description

(S,Z)-12α-Methyloxacyclododeca-4-En-2-One CAS NO 86578-99-6 is a high-purity, specialized macrolide intermediate with a defined stereochemistry. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of macrolide antibiotics and other pharmacologically active compounds.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients with specific biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex fragrance and flavor molecules.
• Academic & Industrial Research: Employed in methodological studies and the development of new asymmetric synthesis routes.
• Material Science: Investigated as a monomer or precursor for specialized polymers with unique properties.

Basic Information

Product Name	(S,Z)-12α-Methyloxacyclododeca-4-En-2-One
CAS No.	86578-99-6
Molecular Formula	C₁₃H₂₂O₂
Molecular Weight	210.31 g/mol
Synonyms	(4Z,12S)-12-Methyloxacyclododec-4-en-2-one; (S,Z)-12-Methyloxacyclododec-4-en-2-one; (-)-Patulolide C Precursor; Macrolide Intermediate 86578-99-6; (12S)-(Z)-12-Methyloxacyclododec-4-en-2-one; (S)-12-Methyl-4-oxacyclododec-4-en-2-one (Z-isomer); Patulolide C Synthetic Intermediate
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR to confirm identity, isomeric purity, and chemical potency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed under an inert atmosphere when handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	≥ 98.0% (S,Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.