Description

β-D-Glucopyranuronic Acid, Methyl Ester, 2,3,4-Tris(2,2-Dimethylpropanoate) is a high-purity, fully protected derivative of glucuronic acid, a key building block in carbohydrate and glycoconjugate chemistry. This compound is engineered to provide exceptional stability and selectivity in complex synthetic pathways, enabling the precise construction of advanced biomolecules. It is an essential intermediate for research and development in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for the synthesis of glycosides, prodrugs, and complex oligosaccharides.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutics.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
• Carbohydrate Chemistry Research: Serves as a protected glucuronyl donor in glycosylation reactions for academic and industrial R&D.
• Prodrug Development: Facilitates the creation of glucuronide prodrugs designed for targeted drug delivery and activation.
• Bioconjugation: Enables the site-specific attachment of carbohydrate motifs to proteins, antibodies, or other biomolecules.
• Standards & Reference Materials: Provides a high-purity standard for analytical method development and quality control in related synthetic processes.

Basic Information

Item	Detail
Product Name	β-D-Glucopyranuronic Acid, Methyl Ester, 2,3,4-Tris(2,2-Dimethylpropanoate)
CAS No.	86448-98-8
Molecular Formula	C₂₄H₄₀O₁₁
Molecular Weight	504.57 g/mol
Synonyms	Methyl (2,3,4-tri-O-pivaloyl-β-D-glucopyranosyl)uronate; Methyl 2,3,4-Tri-O-pivaloyl-β-D-glucopyranosiduronic Acid; β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tripivalate; Piv3-β-D-GlcA-OMe; 2,3,4-Tri-O-pivaloyl-β-D-glucuronic Acid Methyl Ester; Fully Protected Methyl β-D-Glucuronate; Glucuronic Acid Methyl Ester Pivaloyl Derivative
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranuronic Acid, Methyl Ester, 2,3,4-Tris(2,2-Dimethylpropanoate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full traceability are provided to guarantee batch-to-batch consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; the container should be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.