Description

2-(4-(5-Bromo-3-Methylpyrid-2-Yl)Butylamino)-5-(6-Hydroxymethylpyrid-3-Ylmethyl)Pyrimidin-4(1H)-One is a sophisticated heterocyclic organic compound featuring a pyrimidinone core substituted with bromopyridyl and hydroxymethylpyridyl groups. This molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic and cellular pathway studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) optimization in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and bioactivity.

Basic Information

Product Name	2-(4-(5-Bromo-3-Methylpyrid-2-Yl)Butylamino)-5-(6-Hydroxymethylpyrid-3-Ylmethyl)Pyrimidin-4(1H)-One
CAS No.	86181-45-5
Molecular Formula	C21H24BrN5O2
Molecular Weight	458.35 g/mol
Synonyms	2-[4-[(5-Bromo-3-methyl-2-pyridinyl)butyl]amino]-5-[(6-hydroxymethyl-3-pyridinyl)methyl]-4(1H)-pyrimidinone; 5-[(6-Hydroxymethylpyridin-3-yl)methyl]-2-[[4-(5-bromo-3-methylpyridin-2-yl)butyl]amino]pyrimidin-4(1H)-one; CAS 86181-45-5; 86181-45-5
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.