Description

L-Proline, 4-Chloro-, Methyl Ester (9Ci) is a chiral, non-proteinogenic amino acid derivative, specifically a halogenated proline ester. This compound is a valuable synthetic intermediate and building block in organic and medicinal chemistry, prized for its ability to introduce structural complexity and modulate the properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptidomimetics, protease inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate modified amino acid structures.
• Peptide Chemistry: Serves as a protected and functionalized proline analog for the solid-phase and solution-phase synthesis of modified peptides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Asymmetric Catalysis: Can be utilized as a precursor for chiral ligands or catalysts in enantioselective synthesis.
• Material Science: A potential monomer or modifier for creating specialized polymers with unique structural features.

Basic Information

Product Name	L-Proline, 4-Chloro-, Methyl Ester (9Ci)
CAS No.	86029-02-9
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	Methyl (2S)-4-chloropyrrolidine-2-carboxylate; (S)-Methyl 4-chloropyrrolidine-2-carboxylate; L-4-Chloroproline methyl ester; (S)-4-Chloroproline methyl ester; 4-Chloro-L-proline methyl ester; Methyl L-4-chloroproline; Methyl (S)-4-chloroproline; 86029-02-9
EINECS	Contact for details

Quality Control

Our L-Proline, 4-Chloro-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.