Description

Methyl 2-Chloro-4-Fluoro-5-Nitrobenzoate is a versatile and high-purity organic intermediate of significant importance in advanced chemical synthesis. Its value lies in its multifunctional aromatic structure, which serves as a critical building block for constructing more complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides, where the chloro-fluoro-nitro substitution pattern confers specific biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, ester transformations, and nucleophilic aromatic substitutions to introduce functionalized benzoate motifs.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex colorants and functional dyes due to its nitro and ester groups.

Basic Information

Product Name	Methyl 2-Chloro-4-Fluoro-5-Nitrobenzoate
CAS No.	85953-30-6
Molecular Formula	C8H5ClFNO4
Molecular Weight	233.58 g/mol
Synonyms	2-Chloro-4-fluoro-5-nitrobenzoic acid methyl ester; Methyl 2-chloro-4-fluoro-5-nitrobenzoate; Benzoic acid, 2-chloro-4-fluoro-5-nitro-, methyl ester; 5-Nitro-2-chloro-4-fluorobenzoic acid methyl ester; Methyl 5-nitro-2-chloro-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-4-Fluoro-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.