Description

2-Chloro-3-Isocyanato-Pyridine is a versatile and highly reactive heterocyclic building block, specifically an isocyanate derivative of a chlorinated pyridine. This compound is valued for its dual functionality, where the isocyanate group readily undergoes addition reactions with nucleophiles, and the chloro substituent offers a site for further functionalization via cross-coupling or substitution. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in the creation of urea and carbamate derivatives with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for constructing urea and carbamate-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites to create diverse chemical scaffolds.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes and other functional polymers with unique thermal or chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new heterocyclic chemistry, creating chemical libraries for screening, and developing novel synthetic methodologies.
• Material Science: Investigated for the surface modification of materials and the creation of advanced coatings or adhesives with specific performance characteristics.

Basic Information

Product Name	2-Chloro-3-Isocyanato-Pyridine
CAS No.	85915-44-2
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	3-Isocyanato-2-chloropyridine; 2-Chloro-3-pyridyl isocyanate; 2-Chloropyridin-3-yl isocyanate; 2-Chloro-3-pyridinyl isocyanate; Isocyanic acid, 2-chloro-3-pyridinyl ester; 2-Chloro-3-isocyanatopyridine; 2-Chloro-3-pyridine isocyanate
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Isocyanato-Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.