Description

n-Boc-1,2,3,6-Tetrahydropyridine is a versatile and highly valuable protected amine intermediate in organic synthesis. Its primary function is to serve as a key building block for the construction of complex nitrogen-containing heterocycles, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of piperidine-based drug candidates, including potential treatments for neurological disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the tetrahydropyridine scaffold imparts specific biological activity.
• Organic Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions such as alkylation, acylation, and cross-coupling.
• Peptidomimetics Research: Serves as a constrained scaffold in the design of peptide mimics to enhance metabolic stability and bioavailability.
• Catalyst and Ligand Development: Acts as a starting material for synthesizing novel chiral auxiliaries, ligands, and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	n-Boc-1,2,3,6-Tetrahydropyridine
CAS No.	85838-94-4
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	1-Boc-1,2,3,6-Tetrahydropyridine; tert-Butyl 1,2,3,6-tetrahydropyridine-1-carboxylate; N-Boc-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydropyridine-1-carboxylic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridine; 1-N-Boc-1,2,3,6-tetrahydropyridine; Boc-THP
EINECS	Contact for details

Quality Control

Our n-Boc-1,2,3,6-Tetrahydropyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.