Description

Rilmazafone Hydrochloride is a high-purity pharmaceutical intermediate and reference standard. This compound is critical for research and development in the field of benzodiazepine receptor agonists. It is primarily utilized by pharmaceutical manufacturers and analytical laboratories for the synthesis of active pharmaceutical ingredients (APIs) and for quality control testing.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-class active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) testing of pharmaceutical products.
• Biochemical Research: Serves as a potent tool compound for studying GABAA receptor pharmacology and related neurological pathways.
• Preclinical Studies: Employed in the research and development of new therapeutic agents targeting anxiety, sedation, and muscle relaxation.
• Impurity Standard: Used to identify and quantify related substances in pharmaceutical formulations during stability and release testing.

Basic Information

Product Name	Rilmazafone Hydrochloride
CAS No.	85815-37-8
Molecular Formula	C22H23ClN4O3
Molecular Weight	426.90 g/mol
Synonyms	Rilmazafone HCl; 5-[(2-Aminophenyl)methyl]-1,3-dihydro-1-[(4-methyl-1-piperazinyl)carbonyl]-2H-1,4-benzodiazepin-2-one Hydrochloride; 450191P; Probenzodiazepine; 1,3-Dihydro-1-[(4-methyl-1-piperazinyl)carbonyl]-5-(2-aminobenzyl)-2H-1,4-benzodiazepin-2-one Hydrochloride
EINECS	Contact for details

Quality Control

Our Rilmazafone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.