Description

(S)-N,n-Diethyl-5-Oxopyrrolidine-2-Carboxamide CAS NO 85760-88-9 is a high-purity, chiral pyrrolidone derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a specific stereochemical configuration into their target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorder treatments.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries in drug discovery programs targeting protease or receptor modulation.
• Agrochemical Development: Intermediate in the synthesis of novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Building block for creating complex molecules used in flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological studies and process development for organic synthesis.

Basic Information

Product Name	(S)-N,n-Diethyl-5-Oxopyrrolidine-2-Carboxamide
CAS No.	85760-88-9
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	(S)-N,N-Diethyl-2-pyrrolidinone-5-carboxamide; (S)-5-Oxo-N,N-diethylpyrrolidine-2-carboxamide; (2S)-N,N-Diethyl-5-oxopyrrolidine-2-carboxamide; L-Proline, 5-oxo-, N,N-diethylamide; (S)-N,N-Diethyl-5-oxo-2-pyrrolidinecarboxamide; (S)-5-Oxo-1-azabicyclo[3.3.0]octane-2-carboxamide, N,N-diethyl- (related structure); (S)-N-Ethyl-2-pyrrolidinone-5-carboxamide, N-ethyl-
EINECS	Contact for details

Quality Control

Our (S)-N,n-Diethyl-5-Oxopyrrolidine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.