Description

Pyridine, 3-[[(Trimethylsilyl)Oxy]Methyl]- (9Ci) is a specialized organosilicon derivative of pyridine, serving as a valuable protected intermediate in advanced organic synthesis. This compound is particularly significant for its role in introducing functional groups while offering stability and controlled reactivity under specific conditions. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organometallic Chemistry: Used as a ligand precursor or a protected functional group in metal-catalyzed coupling reactions.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, agrochemicals, and advanced materials requiring precise molecular architecture.
• Academic & Industrial Research: A critical reagent for methodological development in organic synthesis and medicinal chemistry research programs.
• Silyl Protection Strategy: Utilized to temporarily protect hydroxyl groups during complex synthetic sequences, allowing for selective transformations elsewhere on the molecule.

Basic Information

Product Name	Pyridine, 3-[[(Trimethylsilyl)Oxy]Methyl]- (9Ci)
CAS No.	85719-72-8
Molecular Formula	C9H15NOSi
Molecular Weight	181.31 g/mol
Synonyms	3-((Trimethylsilyloxy)methyl)pyridine; (Pyridin-3-yl)methanol, trimethylsilyl ether; 3-(Hydroxymethyl)pyridine trimethylsilyl ether; 3-Pyridinemethanol, trimethylsilyl ether; TMS ether of 3-pyridinemethanol; Trimethyl((pyridin-3-yl)methoxy)silane; 3-(Trimethylsilyloxymethyl)pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 3-[[(Trimethylsilyl)Oxy]Methyl]- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.