Description

Mitozolomide is a potent alkylating agent and a key pharmaceutical intermediate in the synthesis of advanced chemotherapeutic agents. Its primary value lies in its role as a critical building block for developing targeted cancer therapies, requiring stringent purity and consistency. This compound is essential for research institutions, pharmaceutical R&D laboratories, and manufacturers focused on oncology drug development and production.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of novel chemotherapeutic drugs and prodrugs.
• Oncology Research: Serves as a key reference standard and active moiety in preclinical cancer research and mechanism of action studies.
• API Synthesis: Critical building block in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for cancer treatment.
• Biochemical Research: Used in studies investigating DNA alkylation, apoptosis induction, and cellular response to alkylating agents.
• Process Development: Employed in scaling up and optimizing manufacturing processes for related anticancer compounds.

Basic Information

Product Name	Mitozolomide
CAS No.	85622-95-3
Molecular Formula	C9H11N5O4
Molecular Weight	253.22 g/mol
Synonyms	8-Carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one; CCRG 81010; M & B 39565; NSC 353451; Imidazotetrazine derivative; Temozolomide analog; 3-(2-Chloroethyl)-8-carbamoyl-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one
EINECS	Contact for details

Quality Control

Our Mitozolomide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.