Description

3-Amino-3-Methyl-Butyric Acid Ethyl Ester Hcl is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of 3-amino-3-methylbutyric acid, serving as a crucial chiral building block in organic synthesis. Its value lies in providing a sterically hindered β-amino acid framework with the amine functionality protected, enabling controlled peptide coupling and the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs), peptidomimetics, and specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in constructing β-peptides and non-natural amino acid scaffolds.
• Peptidomimetics Synthesis: Used to create peptide analogs with enhanced metabolic stability and bioavailability for drug discovery programs.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for introducing the 3-amino-3-methylbutyric acid moiety into target molecules.
• Agrochemical Research: Potential intermediate in the synthesis of advanced crop protection agents and herbicides requiring specific chiral amino acid structures.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing biological systems.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-Amino-3-Methyl-Butyric Acid Ethyl Ester Hcl
CAS No.	85532-40-7
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	Ethyl 3-Amino-3-methylbutanoate Hydrochloride; 3-Amino-3-methylbutyric Acid Ethyl Ester Hydrochloride; 3-Methyl-3-aminobutyric Acid Ethyl Ester HCl; Ethyl 3-Amino-3-methylbutyrate HCl; β-Aminoisovaleric Acid Ethyl Ester Hydrochloride; 3-Amino-3-methyl-butanoic Acid Ethyl Ester Hydrochloride; AMBE-HCl; 3-Amino-3-methylbutanoic Acid Ethyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-3-Methyl-Butyric Acid Ethyl Ester Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, determination of optical rotation where applicable, and verification of identity and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture, which can lead to degradation or clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.