Description

Ethyl 4-Hydroxy-3-Oxobutanoate is a versatile keto-ester building block with significant synthetic utility in organic chemistry. This compound is valued for its bifunctional structure, featuring both a reactive ketone and an ester group, which makes it a key intermediate for constructing complex molecular frameworks. It is primarily sought after by research and development chemists, as well as process development teams, in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for chiral drugs and complex heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for flavors, fragrances, and specialty polymers.
• Academic & Industrial Research: Employed in methodological development for novel organic transformations, including aldol and Michael addition reactions.
• Chiral Auxiliary Synthesis: Useful in the preparation of chiral ligands and catalysts for asymmetric catalysis.

Basic Information

Product Name	Ethyl 4-Hydroxy-3-Oxobutanoate
CAS No.	85518-49-6
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	Ethyl 4-Hydroxy-3-oxobutanoate; Ethyl 4-Hydroxyacetoacetate; 4-Hydroxy-3-oxobutanoic Acid Ethyl Ester; Ethyl 3-Oxo-4-hydroxybutyrate; Ethyl 4-Hydroxy-3-oxobutyrate; 4-Hydroxyacetoacetic Acid Ethyl Ester; 3-Oxo-4-hydroxybutyric Acid Ethyl Ester; Ethyl (R/S)-4-Hydroxy-3-oxobutanoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-3-Oxobutanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.