Description

(E)-1-(4-Chlorophenyl)-3-(4-(Dimethylamino)Phenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure featuring chlorophenyl and dimethylaminophenyl groups. This compound is a critical pharmaceutical intermediate and organic building block valued for its role in the synthesis of more complex bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new therapeutic agents and functional chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its chalcone backbone for biological activity.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport or emissive layer material due to its conjugated system and electron-donating dimethylamino group.
• Nonlinear Optical (NLO) Materials: Investigated for use in photonic devices because of its significant molecular hyperpolarizability.
• Chemical Biology Probe: Utilized in research to study protein-ligand interactions and enzyme inhibition mechanisms.
• Academic & Industrial R&D: Employed as a standard or building block in organic synthesis and medicinal chemistry projects.

Basic Information

Product Name	(E)-1-(4-Chlorophenyl)-3-(4-(Dimethylamino)Phenyl)Prop-2-En-1-One
CAS No.	85460-66-8
Molecular Formula	C17H16ClNO
Molecular Weight	285.77 g/mol
Synonyms	4'-Chloro-4-dimethylaminochalcone; (E)-3-(4-(Dimethylamino)phenyl)-1-(4-chlorophenyl)prop-2-en-1-one; 1-(4-Chlorophenyl)-3-[4-(dimethylamino)phenyl]-2-propen-1-one; 4-Dimethylamino-4'-chlorochalcone; p-Chlorophenyl p-dimethylaminostyryl ketone; NSC 403914; Chalcone derivative 85460-66-8
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Chlorophenyl)-3-(4-(Dimethylamino)Phenyl)Prop-2-En-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), our technical team is available to discuss your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.