Description

(2E)-3-(2-Chlorophenyl)-1-(4-Chlorophenyl)Prop-2-En-1-One is a high-purity, specialized organic intermediate featuring a chalcone backbone with distinct chlorine substitutions. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photonic materials due to its conjugated system and molecular rigidity.
• Chemical Biology Probe: Employed as a building block for creating fluorescent tags or molecular probes to study biological pathways and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	(2E)-3-(2-Chlorophenyl)-1-(4-Chlorophenyl)Prop-2-En-1-One
CAS No.	85460-65-7
Molecular Formula	C15H10Cl2O
Molecular Weight	277.14 g/mol
Synonyms	2',4'-Dichlorochalcone; (E)-1-(4-Chlorophenyl)-3-(2-chlorophenyl)-2-propen-1-one; 3-(2-Chlorophenyl)-1-(4-chlorophenyl)-2-propen-1-one; (E)-3-(2-Chlorophenyl)-1-(4-chlorophenyl)prop-2-en-1-one; NSC 407296; 1-(4-Chlorophenyl)-3-(2-chlorophenyl)-2-propen-1-one; (E)-2',4'-Dichlorochalcone; 2-Chloro-4'-chlorochalcone
EINECS	Contact for details

Quality Control

Our (2E)-3-(2-Chlorophenyl)-1-(4-Chlorophenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.