Description

Cyclopropanecarboxylic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]-, Ethyl Ester is a high-purity, protected amino acid derivative featuring a cyclopropane ring, a key structural motif in advanced organic synthesis. This compound is valued for its role as a sophisticated chiral building block in the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing constrained peptide mimetics and other structurally unique compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly those requiring conformationally restricted peptide backbones.
• Peptidomimetics Research: Used to introduce the rigid cyclopropane scaffold into peptide chains to enhance metabolic stability and receptor selectivity.
• Agrochemical Synthesis: Serves as a key intermediate in the development of advanced pesticides and herbicides with unique modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis Building Block: Provided to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Used in university and institutional laboratories for methodological development in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]-, Ethyl Ester
CAS No.	85452-41-1
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	1-[(Benzyloxycarbonyl)amino]cyclopropanecarboxylic acid ethyl ester; Ethyl 1-[(benzyloxycarbonyl)amino]cyclopropanecarboxylate; Ethyl 1-{[(benzyloxy)carbonyl]amino}cyclopropanecarboxylate; Z-1-Aminocyclopropanecarboxylic acid ethyl ester; Cbz-1-Aminocyclopropanecarboxylic acid ethyl ester; N-Carbobenzoxy-1-aminocyclopropanecarboxylic acid ethyl ester; 1-(N-Cbz-amino)cyclopropanecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.