Description

(E)-Methyl 3-Amino-4,4-Dimethoxybut-2-Enoate CAS NO 85396-57-2 is a high-purity, versatile chemical intermediate featuring an enamine ester structure with protected carbonyl functionality. This compound is valued for its role as a key building block in the synthesis of complex heterocycles and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those containing pyridine, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive amino and ester groups.
• Fine Chemical Production: Serves as a specialized building block for creating complex molecules used in dyes, pigments, and advanced materials.
• Academic & R&D: Employed in organic chemistry research for method development and exploring new reaction pathways involving enamine chemistry.
• Peptidomimetics: The structural motif is useful in the design and synthesis of peptide analogs for biochemical studies.

Basic Information

Product Name	(E)-Methyl 3-Amino-4,4-Dimethoxybut-2-Enoate
CAS No.	85396-57-2
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	Methyl (2E)-3-amino-4,4-dimethoxy-2-butenoate; Methyl 3-Amino-4,4-dimethoxy-2-butenoate; 3-Amino-4,4-dimethoxy-2-butenoic acid methyl ester; (E)-Methyl 3-amino-4,4-dimethoxybut-2-enoate; 2-Butenoic acid, 3-amino-4,4-dimethoxy-, methyl ester, (2E)-; Methyl 3-amino-4,4-dimethoxycrotonate; 85396-57-2; Enamine ester intermediate
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-Amino-4,4-Dimethoxybut-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.