Description

1-tert-Butyl 3-Methyl 2,2-Dimethylmalonate is a high-purity diester derivative of malonic acid, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its role as a protected malonate synthon, enabling controlled alkylation and condensation reactions under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular construction for developing active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring malonate-derived frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific ester groups are required for bioactivity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals that utilize malonate chemistry.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the development of specialized polymers and resins.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex carbon chains and heterocycles via classic malonate alkylation.
• Material Science: Potential use in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-tert-Butyl 3-Methyl 2,2-Dimethylmalonate
CAS No.	85293-46-5
Molecular Formula	C11H20O4
Molecular Weight	216.27 g/mol
Synonyms	2,2-Dimethylmalonic Acid 1-tert-Butyl 3-Methyl Ester; Dimethyl 2,2-Dimethylmalonate (mixed tert-butyl/methyl esters); tert-Butyl Methyl 2,2-Dimethylmalonate; Malonic Acid, 2,2-Dimethyl-, 1-(1,1-Dimethylethyl) 3-Methyl Ester; 2,2-Dimethylpropanedioic Acid tert-Butyl Methyl Ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Methyl 2,2-Dimethylmalonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.