Description

Succinimido-6-n-(4-Azidobenzoyl)Aminohexanoate is a heterobifunctional crosslinking reagent featuring an amine-reactive N-hydroxysuccinimide (NHS) ester and a photoactivatable aryl azide group. This compound is specifically engineered for the controlled conjugation of biomolecules, enabling the formation of stable covalent bonds upon exposure to UV light. It is an essential tool for researchers and manufacturers in bioconjugation, proteomics, and the development of diagnostic assays and targeted therapeutics, where precise and stable linkage of proteins, peptides, or other ligands is required.

Application

• Photochemical crosslinking of proteins to surfaces, membranes, or other biomolecules for affinity purification or microarray development.
• Site-specific labeling and modification of antibodies, enzymes, and other proteins for diagnostic kit manufacturing.
• Preparation of immunoconjugates and antibody-drug conjugates (ADCs) in pharmaceutical research and development.
• Immobilization of biomolecules onto biosensors, chips, or solid supports to create bioactive interfaces.
• Studying protein-protein interactions and mapping binding sites through photoaffinity labeling techniques.
• Conjugation of haptens to carrier proteins for antibody production.
• Functionalization of nanoparticles or polymers with targeting ligands for drug delivery systems.

Basic Information

Product Name	Succinimido-6-n-(4-Azidobenzoyl)Aminohexanoate
CAS No.	85287-37-2
Molecular Formula	C19H22N4O6
Molecular Weight	402.41 g/mol
Synonyms	6-((4-Azidobenzoyl)amino)hexanoic acid N-succinimidyl ester; NHS-PEG4-Azide; N-Succinimidyl 6-((4-azidobenzoyl)amino)hexanoate; SANH; 4-Azidobenzoyl-6-aminocaproic acid N-hydroxysuccinimide ester; Heterobifunctional Crosslinker SANH; N-Succinimidyl 4-azidobenzamidohexanoate; Azido-PEG4-NHS Ester
EINECS	Contact for details

Quality Control

Our Succinimido-6-n-(4-Azidobenzoyl)Aminohexanoate is manufactured under strict quality protocols to ensure high purity and consistent performance for sensitive bioconjugation applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional suitability. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile
Functional Activity	Conforms (by conjugation test)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.