Description

Methyl 2-Bromo-2-(4-Nitrophenyl)Acetate is a versatile brominated aromatic ester building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive bromoacetate group and an electron-withdrawing nitro substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring aryl-acetate or α-bromo carbonyl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the nitrophenyl group is a common bioactive component.
• Organic Synthesis Reagent: Serves as a versatile electrophile in coupling reactions (e.g., Suzuki, Heck) and as a precursor for generating other functional groups via nucleophilic substitution.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe Development: Utilized in creating activity-based probes or affinity labels for studying enzyme function, leveraging its reactive bromo group.

Basic Information

Product Name	Methyl 2-Bromo-2-(4-Nitrophenyl)Acetate
CAS No.	85259-33-2
Molecular Formula	C9H8BrNO4
Molecular Weight	274.07 g/mol
Synonyms	Methyl α-Bromo-4-nitrobenzeneacetate; 2-Bromo-2-(4-nitrophenyl)acetic acid methyl ester; Methyl (4-nitrophenyl)bromoacetate; p-Nitrophenylbromoacetic acid methyl ester; α-Bromo-4-nitrobenzeneacetic acid methyl ester; Methyl 2-bromo-2-(p-nitrophenyl)acetate; Bromo(4-nitrophenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-2-(4-Nitrophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.