Description

3-Amino-5-Bromo-6-Methylpyridin-2-Ol is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex heterocyclic systems, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and amino functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	3-Amino-5-Bromo-6-Methylpyridin-2-Ol
CAS No.	85216-55-3
Molecular Formula	C6H7BrN2O
Molecular Weight	203.04 g/mol
Synonyms	5-Bromo-6-methyl-2-hydroxy-3-pyridinamine; 3-Amino-5-bromo-6-methyl-2(1H)-pyridinone; 2-Hydroxy-3-amino-5-bromo-6-methylpyridine; 5-Bromo-3-amino-6-methylpyridin-2-ol; 5-Bromo-6-methyl-3-aminopyridin-2-ol; 3-Amino-5-bromo-6-methyl-2-pyridinol; 85216-55-3
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromo-6-Methylpyridin-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.