Description

Hydroquinine Hydrobromide Hydrate is a high-purity alkaloid derivative, primarily valued for its role as a key chiral intermediate and resolving agent in asymmetric synthesis. Its significance lies in enabling the production of enantiomerically pure compounds, which is critical for pharmaceutical efficacy and safety. This product is essential for research laboratories, fine chemical manufacturers, and pharmaceutical companies developing active pharmaceutical ingredients (APIs), particularly in the areas of antimalarial and cardiovascular therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex chiral APIs, especially in antimalarial and antiarrhythmic drug development.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids and other compounds in fine chemical and pharmaceutical manufacturing.
• Asymmetric Synthesis Catalyst: Employed in stereoselective reactions to create specific enantiomers with high optical purity.
• Biochemical Research: Serves as a standard or reagent in pharmacological studies and metabolic pathway research.
• Analytical Chemistry: Used as a reference standard in chromatographic methods (HPLC, TLC) for quality control and method development.

Basic Information

Product Name	Hydroquinine Hydrobromide Hydrate
CAS No.	85153-19-1
Molecular Formula	C₂₀H₂₈N₂O₂ • HBr • xH₂O
Molecular Weight	Contact for details
Synonyms	Hydroquinine HBr Hydrate; Dihydroquinine Hydrobromide Hydrate; (8S,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol Hydrobromide Hydrate; Hydroquininium Bromide Hydrate; Quinidine Dihydrobromide Derivative; HCQ-HBr Hydrate
EINECS	Contact for details

Quality Control

Our Hydroquinine Hydrobromide Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, specific rotation for chiral identity, and loss on drying. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0% (anhydrous basis)
Specific Rotation	Contact for details
Loss on Drying	≤5.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.