Description

6-(Dibromomethyl)Picolinonitrile is a versatile brominated heterocyclic building block, essential for advanced organic synthesis. Its unique molecular structure, featuring both a reactive dibromomethyl group and a nitrile-substituted pyridine ring, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the bromomethyl and nitrile functionalities enable structural diversification.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized pyridine-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of functional organic molecules for electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build complex molecular architectures.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-(Dibromomethyl)Picolinonitrile
CAS No.	85148-97-6
Molecular Formula	C7H4Br2N2
Molecular Weight	275.93 g/mol
Synonyms	2-Cyano-6-(dibromomethyl)pyridine; 6-(Dibromomethyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 6-(dibromomethyl)-; Picolinonitrile, 6-(dibromomethyl)-; 6-(Dibromomethyl)-2-cyanopyridine; (6-(Dibromomethyl)pyridin-2-yl)methanenitrile
EINECS	Contact for details

Quality Control

Every batch of 6-(Dibromomethyl)Picolinonitrile is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.